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Sunday, September 03, 2006 | Nanoparticles | 0 comments
Antibody-Dendrimer Combo Penetrates Cancer Cells Faster Than Antibody Alone
Dendrimers are highly branched, spherical polymers that form well-defined, biocompatible nanoparticles.

Sunday, September 03, 2006 | Nanoparticles | 0 comments
Nanoparticles Successfully Deliver Protein-Suppressing RNA-Based Therapies
Two reports in the journal Clinical Cancer Research now show that nanoparticles may be the vehicle of choice for delivering these agents into tumor cells.

Sunday, August 27, 2006 | Nanoparticles | 0 comments
Study Tracks Magnetic Nanoparticles Targeting Breast Tumors
An in-depth study of nanoparticle distribution in tumor-bearing mice has shown that targeted magnetic nanoparticles accumulate and cluster in both primary breast tumors and metastatic lesions that have developed in the lung.

Sunday, August 27, 2006 | Nanoparticles | 0 comments
Nanoparticle Enables Light-Activated Ovarian Cancer Detection and Therapy
By combining a compound produced by the plant St. John’s wort with polymeric nanoparticles, researchers at the University of Geneva in Switzerland have developed a promising method for treating ovarian tumors using light.

Sunday, August 27, 2006 | Nanoparticles | 0 comments
Nanoparticle Design Influences Inflammatory Potential in Lung
Drug developers consider the lungs to be an excellent route through which to administer drugs. Many studies have shown that inhaled nanoparticles, including those from natural sources, can trigger inflammation in the lungs, raising concerns that have slowed efforts to develop inhalable nanoparticle drug delivery systems for anticancer agents.

Wednesday, August 23, 2006 | Nanoparticles | 0 comments
New Methods for Screening Nanoparticles
Scientists at the U.S. Department of Energy’s Brookhaven National Laboratory have developed a screening method to examine how newly made nanoparticles — particles with dimensions on the order of billionths of a meter — interact with human cells following exposure for various times and doses.

Tuesday, August 15, 2006 | Nanoparticles | 0 comments
Nanoparticles slip through blood vessel pores to attack tumor
Fatty spheres loaded with siRNA shrink ovarian cancer tumors in preclinical trial

Sunday, August 13, 2006 | Nanoparticles | 0 comments
Nanoparticle-Drug Combo Stops Tumor-Associated Angiogenesis
By encapsulating a drug already approved to treat a side effect of cancer inside liposomal nanoparticles, researchers at the University of Zürich have developed an agent that stops tumor-associated angiogenesis and reduces tumor growth by as much as 92 percent.

Sunday, August 13, 2006 | Nanoparticles | 0 comments
Nanoparticles Deliver Gene-Silencing RNA
Work from the University of Aarhus, in Denmark, shows that nanoparticles may serve as suitable delivery vehicles for siRNA.

Sunday, August 06, 2006 | Nanoparticles | 0 comments
Intracellular Tracking with Coated Gold Nanoparticles
Gold nanoparticles, with their novel optical and physical properties, have rapidly become a favorite tool of biomedical researchers, yet their ultimate utility in cancer research and clinical oncology depends on an ability to stably link them to targeting molecules and drugs

Wednesday, August 02, 2006 | Nanoparticles | 0 comments
Tiny inhaled particles take easy route from nose to brain
University of Rochester Medical Center scientists showed that when rats breathe in nano-sized materials they follow a rapid and efficient pathway from the nasal cavity to several regions of the brain

Sunday, July 30, 2006 | Nanoparticles | 0 comments
Antibody Targeting Boosts Nanoparticle Uptake by Tumor Cells
New data from investigators at the University of California, San Francisco, shows that antibody targeting actually causes cancer cells to take up the attached nanoparticles, increasing the amount of drug inside tumor cells.

Sunday, July 30, 2006 | Nanoparticles | 0 comments
For Anticancer Nanoparticles, Two Targets Are Better than One
One of the advantages of using nanoparticles as delivery devices for therapeutic and imaging agents is the ability to attach a wide variety of tumor-targeting molecules to the nanoparticle surface.

Wednesday, July 26, 2006 | Nanoparticles | 0 comments
UCSF Scientists Use Nanotechnology to Increase the Amount of Drug Uptake by Tumor Cells
Several studies have shown that antibody-targeting of drug-laden nanoparticles to cancer cell receptors can significantly enhance antitumor efficacy of the drug cargo.

Sunday, July 16, 2006 | Nanoparticles | 0 comments
Metal-Organic Hybrids Yield Versatile Nanoparticle-Based Imaging Agents
By combining the properties of inorganic and organic molecules in one material, researchers at the Carolina Center of Cancer Nanotechnology Excellence (CCNE) have developed a new class of nanomaterials that can be used to create multifunctional nanoparticles

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